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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 623651Generated: October 29, 2026

1-[3-(Trifluoromethoxy)phenyl]ethan-1-amine → Methyl 6-methyl-4-((1-(3-(trifluoromethoxy)phenyl)ethyl)carbamoyl)picolinate

https://huagongshe.com/reaction/623651

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[3-(Trifluoromethoxy)phenyl]ethan-1-amineHCID 22605542—
Reactant2-(Methoxycarbonyl)-6-methylisonicotinic acidHCID 59570879—
ProductMethyl 6-methyl-4-((1-(3-(trifluoromethoxy)phenyl)ethyl)carbamoyl)picolinateHCID 67510274—

Reaction Steps

The title compound is prepared from (+)-1-(3-(trifluoromethoxy)phenyl)ethanamine (Amine-9) and 2-(methoxycarbonyl)-6-methylisonicotinic acid by the similar manner in Step-1 of Example 8.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09302991B2
Source datasetuspto-grants-2016_04
ORD IDord-6321dac7a98f4d7e826a094c8444fb55
Source noteuspto-grants-2016_04