反应详情

NBS (2.14 g, 12 mmol) and AgNO3 (170 mg, 1 mmol) were added to a solution of triisopropylsilylacetylene (2.24 ml, 10 mmol) in acetone (15 ml). The solution was stirred for 2 hours at RT. Pentane (20 ml) and H2O (20 ml) were added and the solution was stirred for 30 minutes. The organic phase was extracted with pentane (3×20 ml) and dried over Na2SO4. The solvent was removed under reduced pressure at RT and the residue was used in the next reaction without any purification.

1. stirringthe solution was stirred for 30 minutes
2. extractionThe organic phase was extracted with pentane (3×20 ml)
3. dry with materialdried over Na2SO4
4. customThe solvent was removed under reduced pressure at RT
5. customthe residue was used in the next reaction without any purification