HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 3-hydroxy-2,2-dimethylpropanoate → Tert-butyl 3-[(5-chloropyrazin-2-yl)oxy]-2,2-dimethylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 3-hydroxy-2,2-dimethylpropanoate | HCID 54272639 | — |
| Reactant | HCID 178516772 | HCID 178516772 | — |
| Product | Tert-butyl 3-[(5-chloropyrazin-2-yl)oxy]-2,2-dimethylpropanoate | HCID 86698186 | 84.2% |
Reaction Steps
By using 5-chloropyrazin-2-ol (700 mg) and tert-butyl hydroxypivalate (1402 mg), the procedure was carried out in the same manner as in Example 1-1) to obtain tert-butyl 3-[(5-chloropyrazin-2-yl)oxy]-2,2-dimethylpropanoate (1294.5 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302996B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-54c06b1614b54d93b0733a35754b93eb |
| Source note | uspto-grants-2016_04 |