(1-Methyl-1H-imidazol-5-yl)(6-(trifluoromethyl)pyridin-3-yl)methanone → (2-(Azetidin-1-yl)-4-chloro-3-(4-chlorophenoxy)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(6-(trifluoromethyl)pyridin-3-yl)methanol

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	(1-Methyl-1H-imidazol-5-yl)(6-(trifluoromethyl)pyridin-3-yl)methanone	HCID 86715442	—
Edukt	2-(Azetidin-1-yl)-6-bromo-4-chloro-3-(4-chlorophenoxy)quinoline	HCID 86715464	—
Produkt	(2-(Azetidin-1-yl)-4-chloro-3-(4-chlorophenoxy)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(6-(trifluoromethyl)pyridin-3-yl)methanol	HCID 86715463	—

Reaktionsschritte

The title compound was prepared using 2-(azetidin-1-yl)-6-bromo-4-chloro-3-(4-chlorophenoxy)quinoline (Intermediate 9, step d) and (1-methyl-1H-imidazol-5-yl)(6-(trifluoromethyl)pyridin-3-yl)methanone (Intermediate 2, step c) according to the procedure of

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US09303015B2
Quelldatensatz	uspto-grants-2016_04
ORD ID	ord-97de5061b83d4395abee201f6be74d02
Quellennotiz	uspto-grants-2016_04