反应详情

温度

90 °C

A suspension of 4-chloro-3-nitrobenzenesulfonamide (1.664 g) triethylamine (2 mL) and 1-isopropylpiperidin-4-amine (1 g) in dioxane (10 mL) was stirred for 16 hours at 90° C. The reaction mixture was cooled to room temperature and the solid material was filtered off. The solid material was washed with 20% methanol/dichloromethane, and the mixture was dried under vacuum, to provide the product.

1. temperatureThe reaction mixture was cooled to room temperature
2. filtrationthe solid material was filtered off
3. washThe solid material was washed with 20% methanol/dichloromethane
4. customthe mixture was dried under vacuum
5. customto provide the product