Ethanol → HCID 71223230, compound

Participants

Reaction Steps

To a solution of compound 3-(cyclopropanecarbonyl)-4-oxocyclohexanecarboxylic acid (36.0 g, 0.15 mol) in EtOH (95%, 300 mL) was added hydrazine hydrate (23.0 g, 0.39 mol) at 0° C. The reaction mixture was stirred 18 h at rt. The solvent was concentrated in vacuum to give methyl 3-cyclopropyl-4,5,6,7-tetrahydro-1H-indazole-5-carboxylate (35.0 g). The compound was used in the next reaction without further purification.

Provenance & Evidence