2-Bromo-4-chloro-1,3-thiazole → 3-(6-(3-((tert-Butyldimethylsilyl)oxy)-2-(2-(4-chlorothiazol-2-yl)-2-oxoethoxy)propyl)-1,3-dimethyl-2,4-dioxo-2,3,4,6-tetrahydro-1H-pyrrolo[3,4-d]pyrimidin-5-yl)benzonitrile

Participants

Reaction Steps

The title compound was prepared from 2-((1-((tert-butyldimethylsilyl)oxy)-3-(5-(3-cyanophenyl)-1,3-dimethyl-2,4-dioxo-3,4-dihydro-1H-pyrrolo[3,4-d]pyrimidin-6(2H)-yl)propan-2-yl)oxy)-N-methoxy-N-methylacetamide and 2-bromo-4-chlorothiazole analogously to Example 13, step 3;

Provenance & Evidence