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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 624591Generated: October 30, 2026

3-Methylbenzoyl chloride → 6-(2-Aminoethyl)-1,3-dimethyl-5-(m-tolyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

https://huagongshe.com/reaction/624591

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methylbenzoyl chlorideHCID 74375—
Reactant6-(2-Amino-ethyl)-1,3-dimethyl-5-phenyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dioneHCID 86722879—
Product6-(2-Aminoethyl)-1,3-dimethyl-5-(m-tolyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dioneHCID 86722912—

Reaction Steps

This compound was prepared analogously to Intermediate A by replacing benzoyl chloride (step 2) with 3-methylbenzoyl chloride (commercial).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09303035B2
Source datasetuspto-grants-2016_04
ORD IDord-56dd3a7c86b04ba3b33484f107cd153c
Source noteuspto-grants-2016_04