Methyl 3-bromobenzoate → HCID 86722921, compound

HRID 624600Notes

Reaction equation

HRID 624600 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]1[C:12]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15](Cl)[CH:14]=2)=[C:11]2[C:6]([N:7]([CH3:23])[C:8](=[O:22])[N:9]([CH3:21])[C:10]2=[O:20])=[CH:5]1.BrC1C=C(C=CC=1)[C:28]([O:30][CH3:31])=[O:29]>>[NH2:1][CH2:2][CH2:3][N:4]1[C:12]([C:13]2[CH:14]=[C:15]([CH:16]=[CH:17][CH:18]=2)[C:28]([O:30][CH3:31])=[O:29])=[C:11]2[C:6]([N:7]([CH3:23])[C:8](=[O:22])[N:9]([CH3:21])[C:10]2=[O:20])=[CH:5]1

Participants

3

Reactant 2

HCID 12070Methyl 3-bromobenzoateHCID 867228806-(2-Amino-ethyl)-5-(3-chloro-phenyl)-1,3-dimethyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione

Product 1

HCID 86722921HCID 86722921, compound

Procedure

The title compound was prepared analogously to Intermediate B by replacing 1-bromo-3-chlorobenzene with methyl 3-bromobenzoate;

Sources & evidence

ORD record
ord-112a862740a54cfbb764fab5d46723dd
Source dataset
uspto-grants-2016_04
Patent number
US09303035B2

Reaction notes

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