HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Iodo-4-methyl-1,3-thiazole → 1,3-dimethyl-5-(4-methylthiazol-2-yl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Iodo-4-methyl-1,3-thiazole | HCID 23154594 | — |
| Reactant | 3-(1,3-Dimethyl-2,4-dioxo-2,3,4,6-tetrahydro-1H-pyrrolo[3,4-d]pyrimidin-5-yl)benzonitrile | HCID 86722928 | — |
| Product | 1,3-dimethyl-5-(4-methylthiazol-2-yl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione | HCID 136348395 | — |
Reaction Steps
The title compound was prepared by an analogous method to 3-(1,3-dimethyl-2,4-dioxo-2,3,4,6-tetrahydro-1H-pyrrolo[3,4-d]pyrimidin-5-yl)benzonitrile (Intermediate Ga) by replacing 3-bromobenzonitrile (step 3) with 2-iodo-4-methylthiazole (Intermediate F).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09303035B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-dd01b60a359c4983a6ade2779415235c |
| Source note | uspto-grants-2016_04 |