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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 624641Generated: October 30, 2026

1-Isopropylhydrazine hydrochloride → 9-Bromo-2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine

https://huagongshe.com/reaction/624641

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Isopropylhydrazine hydrochlorideHCID 85573—
Reactant9-bromo-N-(1-iminoethyl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamideHCID 135743665—
SolventAcetic AcidHCID 176—
Product9-Bromo-2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepineHCID 58204322—

Reaction Steps

9-Bromo-N-(1-iminoethyl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide 29 was reacted with isopropylhydrazine hydrochloride 4 in acetic acid to give III.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09303043B2
Source datasetuspto-grants-2016_04
ORD IDord-5d571b1286f942ebbc18b331a524c739
Source noteuspto-grants-2016_04