HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) → HCID 178464915, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Reactant | 9-Bromo-5,6-dihydrobenzo[F]imidazo[1,2-D][1,4]oxazepine-2-carboxylic acid | HCID 58204351 | — |
| Reactant | N'-isopropylacetohydrazonamide | HCID 74037752 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178464915 | HCID 178464915 | — |
Reaction Steps
Coupling of 28 with N′-isopropylacetohydrazonamide 6 and coupling reagent HBTU in DMF gives intermediate, 9-bromo-N-(1-(2-isopropylhydrazinyl)ethylidene)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide 34, which forms III upon heating.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09303043B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-97a86545a9984651b823467175a93be7 |
| Source note | uspto-grants-2016_04 |