HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 624653Generated: October 30, 2026
Hydrochloric Acid → HCID 90031490, compound
https://huagongshe.com/reaction/624653
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 90031146 | HCID 90031146 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | HCID 90031490 | HCID 90031490 | — |
Reaction Steps
To a solution of methyl 1-(pyrimidin-5-yl)-1H-indole-3-carboxylate (16 mg, 0.063 mmol) in water MeOH (316 μl) was added 2M KOH (158 μl, 0.316 mmol). The mixture was heated at 80° C. for 4 h then neutralized with 1M HCl. The precipitate was collected by filtration to afford the title compound as a white solid, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09303045B2 |
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| Source dataset | uspto-grants-2016_04 |
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| ORD ID | ord-d36b82add2bb4dd6825d02fd71a51c86 |
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| Source note | uspto-grants-2016_04 |
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