huagongshe.com
HRID624865

反应详情

EQUATION

反应方程式

HRID 624865 的结构方程式

REACTANTS

反应物

4
结构：CC1(C)COCN1
HCID62010

4,4-Dimethyl oxazolidine

C5H11NO

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F
HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

结构：O=C(O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1
HCID71087292

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)COCN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1
HCID76283337

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with 4,4-dimethyloxazolidine (CAN 51200-87-4) in the presence of TBTU and DIEA to obtain the title compound as white solid; MS (EI): m/e=368.5 [MH+].