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HRID624875

反应详情

EQUATION

反应方程式

HRID 624875 的结构方程式

REACTANTS

反应物

3
结构：ClCc1ccccc1
HCID7503

Benzyl chloride

C7H7Cl

结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：O=C(NC1(C(F)(F)F)CC1)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1
HCID71105762

未命名化合物

PRODUCTS

生成物

1
结构：O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N(Cc1ccccc1)C1(C(F)(F)F)CC1
HCID76283580

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in Example 16 b), 6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)-N-(1-(trifluoromethyl)cyclopropyl)picolinamide (Example 16 a) was reacted with (chloromethyl)benzene (CAN 27987-13-9) in the presence of sodium hydride to give the title compound as colorless oil; MS (EI): m/e=482.4 [MH]+.