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HRID624891

反应详情

EQUATION

反应方程式

HRID 624891 的结构方程式

REACTANTS

反应物

3
结构：CI
HCID6328

Methyl iodide

CH3I

结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：Cc1nc([C@H](CC2CC2)NC(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)no1
HCID71105617

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc([C@H](CC2CC2)N(C)C(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)no1
HCID118458631

未命名化合物

PROCEDURE

实验过程

In analogy to the procure described in Example 16 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid [(S)-2-cyclopropyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide was reacted with methyl iodide (CAN 74-88-4) in the presence of sodium hydride to give the title compound as colorless oil; MS (EI): m/e=448.2 [MH]+.