HRID624930

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID45158909

4,4-Difluoro-L-prolinamide--hydrogen chloride (1/1)

C5H9ClF2N2O

HCID71087346

未命名化合物

PRODUCTS

生成物

结构：NC(=O)[C@@H]1CC(F)(F)CN1C(=O)c1ccc(C2CC2)c(OCC2CC2)n1

HCID90203444

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 47 b, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 3 c, 50 mg, 214 μmol) and (2S)-4,4-difluoro-2-pyrrolidinecarboxamide hydrochloride (CAN 426844-51-1; 44 mg, 236 μmol) as starting materials and isolated (63 mg, 80%) as off-white solid; LC-MS (UV peak area, ESI) 100%, 366.1629 [MH+].

WORKUP

后处理

customisolated (63 mg, 80%) as off-white solid