Hydrochloric Acid → HCID 90203546, compound

Participants

Reaction Steps

A solution of 2-carbamoyl-4,4-dimethyl-pyrrolidine-1-carboxylic acid tert-butyl ester (1.2 g, 4.95 mmol) in dioxane (5 mL) was cooled to 10° C. Hydrogen chloride dissolved in dioxane (10 mL, 6.4 N) was added and the mixture was stirred for 1.5 hours. Diethylether (50 mL) was added to completely precipitate the product, which was filtered and dried to give the title compound (0.84 g, 95%) as colorless solid; MS (ESI) 143.0 [MH+].

Provenance & Evidence