HRID624966

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID81531

Diisopropylethylamine

C8H19N

反应SMILES：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F

HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

HCID12919210

未命名化合物

反应SMILES：O=C(O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1

HCID71087292

未命名化合物

PRODUCTS

产物

反应SMILES：CN(CC1CC1)C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1

HCID76281066

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with 1-cyclopropyl-N-methylmethanamine hydrochloride (77335-18-3) in the presence of TBTU and DIEA to obtain the title compound as colorless oil; MS (EI): m/e=352.4 [MH+].