huagongshe.com
HRID624968

反应详情

EQUATION

反应方程式

HRID 624968 的结构方程式

REACTANTS

反应物

4
结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F
HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

结构：CCOC(=O)C1C2CNCC21
HCID3522274

3-Azabicyclo[3.1.0]hexane-6-carboxylic acid, ethyl ester

C8H13NO2

结构：O=C(O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1
HCID71087292

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)C1C2CN(C(=O)c3ccc(N4CC(F)(F)C4)c(OCC4CC4)n3)CC21
HCID90203999

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with ethyl 3-azabicyclo[3.1.0]hexane-6-carboxylate (179236-79-4) in the presence of TBTU and DIEA to obtain the title compound as colorless oil; MS (EI): m/e=422.5 [MH+].