Hydrochloric Acid → HCID 90203343, compound

Participants

Reaction Steps

A solution of (2S)-tert-butyl 2-carbamoyl-4-hydroxy-4-methylpyrrolidine-1-carboxylate (Example 132 a, 46 mg, 188 μmol) in a solution of 4 M HCl in dioxane (942 μL, 3.8 mmol) was stirred at ambient temperature for 5 h. The solvent was removed in vacuo to give the title compound (36 mg, quant.) as light brown solid, MS (ESI) m/e=145.2 [MH+].

Provenance & Evidence