Butyl bromide → N,N,N',N',N'',N''-hexa-n-butylguanidinium bromide

Participants

Reaction Steps

A mixture of 1.7 grams (5 mmol) of penta-n-butylguanidine (made as described earlier), 0.686 grams (5 mmol) of 1-bromobutane and 10 ml of isobutyronitrile was heated under reflux for 20 hours. Upon vacuum stripping, a pale yellow oil was obtained which crystallized to a pale brown solid upon standing. Upon recrystallization from a mixture of hexane and ethyl acetate, the desired N,N,N′,N′,N″,N″-hexa-n-butylguanidinium bromide was obtained as a white solid.

Provenance & Evidence