Hydrochloric Acid → HCID 178443037, compound

Participants

Reaction Conditions

Reaction Steps

Hexadecylamine (3 g, 12.4 mmol) was dissolved in 1-butanol (10 ml) and 37% hydrochloric acid (1.23 g, 12.4 mmol) added. The solution was warmed to 95° C. and cyanamide (0.522 g, 12.4 mmol) dissolved in 1-butanol (20 ml) added dropwise with stirring over 10 minutes. The solution was stirred at 95° C. for a further 2 hours. Solvent was removed and the crude product crystallised from ethyl acetate to give a white solid of N-hexadecylguanidinium chloride.

Provenance & Evidence