反应详情

Thereafter, 20 g (0.066 mol) of 4-(diphenylamino)benzaldehyde (1) dissolved in 40 ml of THF was charged into the dropping funnel, and was gradually added dropwise to the mixture. After the addition, a reaction was caused at room temperature for 2 hours. Then, 70 ml of water was added thereto. The product was extracted with ethyl acetate, and the extract was washed with water until neutralized. The organic phase was dried, concentrated and then purified by column chromatography. Pale yellow crystals of 4-(diphenylamino)styrene (3) (16 g, yield: 89%) was obtained.

1. additionwas charged into the dropping funnel
2. additionwas gradually added dropwise to the mixture
3. additionAfter the addition
4. extractionThe product was extracted with ethyl acetate
5. washthe extract was washed with water
6. customThe organic phase was dried
7. concentrationconcentrated
8. custompurified by column chromatography