Hydrochloric Acid → HCID 131737194, compound

HRID 62556Notes

Reaction equation

HRID 62556 reaction equation
[CH3:1][N:2]([CH3:23])[CH2:3][CH2:4][C@H:5]([NH:15]C(=O)OCC(C)C)[CH2:6][NH:7]C(=O)OCC(C)C.[ClH:24]>>[CH3:1][N:2]([CH3:23])[CH2:3][CH2:4][C@H:5]([NH2:15])[CH2:6][NH2:7].[ClH:24]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 131737195HCID 131737195, compound

Product 1

HCID 131737194HCID 131737194, compound

Procedure

A round bottom flask was charged with (S)-diisobutyl (4-(dimethylamino)butane-1,2-diyl)dicarbamate (0.9 g, 2.7 mmol) and 6 M HCl (50 mL). The reaction mixture was refluxed for 50 h. The acidic solvent was evaporated in vacuum and the hydrochloride salt (S)—N4,N4-dimethylbutane-1,2,4-triamine was obtained as sticky solid (0.607 g). The compound was highly hygroscopic.

Workup

  1. temperatureThe reaction mixture was refluxed for 50 h
  2. customThe acidic solvent was evaporated in vacuum

Sources & evidence

ORD record
ord-7a8a5f7e7579457cb2acd45859027a48
Source dataset
uspto-grants-2016_09
Patent number
US09446393B2

Reaction notes

Loading…