反应详情

4-ethyl-2-methoxy-1-[4-nitro-2-(trifluoromethyl)phenoxy]benzene (1.90 mmol; 651 mg) was dissolved in anhydrous THF (8 mL) under argon. Palladium on charcoal (0.095 mmol; 20 mg) was added and the reaction was flushed twice with hydrogen, then left to stir overnight. The reaction mixture was filtered on celite, rinsed with methanol (3*10 mL). Concentration yielded a light brown oil (579 mg; 98%) used without further purification.

1. customthe reaction was flushed twice with hydrogen
2. waitleft
3. filtrationThe reaction mixture was filtered on celite
4. washrinsed with methanol (3*10 mL)
5. concentrationConcentration
6. customyielded a light brown oil (579 mg; 98%)
7. customused without further purification