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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 626065Generated: October 30, 2026

Tetrahydrofuran → HCID 59191347, compound

https://huagongshe.com/reaction/626065

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantHCID 59191402HCID 59191402—
SolventEthanolHCID 702—
ProductHCID 59191347HCID 5919134742.3%

Reaction Steps

According to the procedure of example 20 (b) except substituting 4-ethyl-2-methoxy-1-[4-nitro-2-(trifluoromethyl) phenoxy]benzene for 4-(2-Benzyloxy-4-ethyl-phenoxy)-3-fluoro-N-(3-imidazol-1-yl-propyl)-benzenesulfonamide (160 mg; 0.31 mmol) and tetrahydrofurane for ethanol (3 mL), the title compound (55 mg; 42%) was obtained as a clear oil, after purification via preparative TLC (dichloromethane/methanol/triethylamine)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09309179B2
Source datasetuspto-grants-2016_04
ORD IDord-e7f1376a3d7441f78eee46697f7393a1
Source noteuspto-grants-2016_04