HuagongsheHuagongshe Chemistry Print Report · For research reference only
[4-(2-Chloroethoxy)phenyl](4-hydroxyphenyl)methanone → HCID 178441050, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [4-(2-Chloroethoxy)phenyl](4-hydroxyphenyl)methanone | HCID 89656364 | — |
| Reactant | HCID 178458546 | HCID 178458546 | — |
| Product | HCID 178441050 | HCID 178441050 | — |
Reaction Steps
Following general procedure of McMurry reaction as described in example 1, step B, 1-(6-hydroxypyridin-3-yl)propan-1-one (0.3 g, 1.0 eq) was reacted with (4-(2-chloroethoxy)phenyl)(4-hydroxyphenyl)methanone (1.37 g, 2.5 eq) to give the desired Z-product (Z and E isomer can be separated via column chromatography).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309211B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-b6d61682dbc64fc182da9b954492794f |
| Source note | uspto-grants-2016_04 |