Lithium hydroxide, monohydrate → HCID 72195631, compound

HRID 626338Notes

Reaction equation

HRID 626338 reaction equation
[NH2:1][CH2:2][C:3]1[CH:4]=[C:5]([C:9]2[CH:10]=[C:11]([C:19]([NH:21][C:22]3[CH:23]=[C:24](/[CH:29]=[CH:30]/[C:31]([O:33]CC)=[O:32])[CH:25]=[CH:26][C:27]=3[F:28])=[O:20])[C:12]3[C:17]([CH:18]=2)=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH:6]=[CH:7][CH:8]=1.O[Li].O>>[NH2:1][CH2:2][C:3]1[CH:4]=[C:5]([C:9]2[CH:10]=[C:11]([C:19]([NH:21][C:22]3[CH:23]=[C:24](/[CH:29]=[CH:30]/[C:31]([OH:33])=[O:32])[CH:25]=[CH:26][C:27]=3[F:28])=[O:20])[C:12]3[C:17]([CH:18]=2)=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 117951652HCID 117951652, compound

Product 1

HCID 72195631HCID 72195631, compound

Procedure

Compound 17d was synthesized from 16d (1 g crude) and LiOH.H2O (8.94 mmol) using the procedure according to Method E described above.

Sources & evidence

ORD record
ord-958251eb6ebf4cd685615754a1d365da
Source dataset
uspto-grants-2016_04
Patent number
US09309187B2

Reaction notes

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