Lithium hydroxide, monohydrate → HCID 72195633, compound

HRID 626340Notes

Reaction equation

HRID 626340 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]([O:12]CC)=[O:11])=[CH:4][C:3]=1[NH:15][C:16]([C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:21]=[C:20]([C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([CH2:34][OH:35])[CH:29]=2)[CH:19]=1)=[O:17].O[Li].O>>[F:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]([OH:12])=[O:11])=[CH:4][C:3]=1[NH:15][C:16]([C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:21]=[C:20]([C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([CH2:34][OH:35])[CH:29]=2)[CH:19]=1)=[O:17]

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 117951647HCID 117951647, compound

Product 1

HCID 72195633HCID 72195633, compoundYield 27.86%

Procedure

Compound 17f (27.86%) was synthesized from 16f (0.89 mmol) and LiOH.H2O (8.94 mmol) using the procedure according to Method E described above.

Sources & evidence

ORD record
ord-117dac77d63e48508d1445fd06cac67d
Source dataset
uspto-grants-2016_04
Patent number
US09309187B2

Reaction notes

Loading…