Lithium hydroxide, monohydrate → HCID 72195766, compound

HRID 626343Notes

Reaction equation

HRID 626343 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([O:12]CC)=[O:11])=[CH:4][C:3]=1[NH:15][C:16]([C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:21]=[C:20]([C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([F:34])[CH:29]=2)[CH:19]=1)=[O:17].O[Li].O>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])=[CH:4][C:3]=1[NH:15][C:16]([C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:21]=[C:20]([C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([F:34])[CH:29]=2)[CH:19]=1)=[O:17]

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 90057964HCID 90057964, compound

Product 1

HCID 72195766HCID 72195766, compoundYield 41.57%

Procedure

Compound 20 was synthesized from 19 (3.26 mmol) and LiOH.H2O (32.6 mmol) using the procedure according to Method E described above.

Sources & evidence

ORD record
ord-287a66ae75d147e4808321000a9f83c7
Source dataset
uspto-grants-2016_04
Patent number
US09309187B2

Reaction notes

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