Lithium hydroxide, monohydrate → HCID 72195769, compound

HRID 626346Notes

Reaction equation

HRID 626346 reaction equation
[N:1]1([C:7]2[CH:8]=[C:9]([C:13]3[CH:14]=[C:15]([C:23]([NH:25][C:26]4[CH:27]=[C:28](/[CH:32]=[CH:33]/[C:34]([O:36]CC)=[O:35])[CH:29]=[CH:30][CH:31]=4)=[O:24])[C:16]4[C:21]([CH:22]=3)=[CH:20][CH:19]=[CH:18][CH:17]=4)[CH:10]=[CH:11][CH:12]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.O[Li].O>>[N:1]1([C:7]2[CH:8]=[C:9]([C:13]3[CH:14]=[C:15]([C:23]([NH:25][C:26]4[CH:27]=[C:28](/[CH:32]=[CH:33]/[C:34]([OH:36])=[O:35])[CH:29]=[CH:30][CH:31]=4)=[O:24])[C:16]4[C:21]([CH:22]=3)=[CH:20][CH:19]=[CH:18][CH:17]=4)[CH:10]=[CH:11][CH:12]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 117951660HCID 117951660, compound

Product 1

HCID 72195769HCID 72195769, compoundYield 75%

Procedure

Compound 25b (107 mg, 75%) was synthesized from 24c (150 mg, 0.3 mmol) and LiOH.H2O (38 mg, 0.89 mmol) using procedure according to the Method E described above.

Sources & evidence

ORD record
ord-5dc811dba398493399e1670a4d40bba5
Source dataset
uspto-grants-2016_04
Patent number
US09309187B2

Reaction notes

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