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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 626469Generated: October 29, 2026

Sodium Hydroxide → HCID 72192659, compound

https://huagongshe.com/reaction/626469

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 72192371HCID 72192371—
ProductHCID 72192659HCID 72192659132%

Reaction Conditions

Temperature105 °C

Reaction Steps

The mixture of ethyl 2-((4-morpholinophenyl)amino)-6-oxo-1,6-dihydropyrimidine-5-carboxylate (210 mg, 0.610 mmol) and sodium hydroxide (1M) were heated at 105° C. for 4 hours followed by heating at 40° C. overnight. Then the solution was condensed to recover the final product (290 mg, 132% yield). 1H-NMR confirmed the product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09309232B2
Source datasetuspto-grants-2016_04
ORD IDord-809d034bfb6c4d568b60fb2fee742cac
Source noteuspto-grants-2016_04