Benzonitrile, 2-amino-3-chloro-5-nitro- → HCID 178510232, compound

HRID 626770Notes

Reaction equation

HRID 626770 reaction equation
[N:1]([C:4]1[C:9]([F:10])=[CH:8][N:7]=[CH:6][C:5]=1/[CH:11]=[N:12]/[C:13]1[C:18](Cl)=[CH:17][C:16]([N+:20]([O-:22])=[O:21])=[CH:15][C:14]=1[Cl:23])=[N+:2]=[N-:3].[NH2:24][C:25]1C(Cl)=CC([N+]([O-])=O)=CC=1C#N>>[N:1]([C:4]1[C:9]([F:10])=[CH:8][N:7]=[CH:6][C:5]=1/[CH:11]=[N:12]/[C:13]1[C:14]([Cl:23])=[CH:15][C:16]([N+:20]([O-:22])=[O:21])=[CH:17][C:18]=1[C:25]#[N:24])=[N+:2]=[N-:3]

Participants

3

Reactant 2

HCID 88504Benzonitrile, 2-amino-3-chloro-5-nitro-HCID 178514520HCID 178514520, compound

Product 1

HCID 178510232HCID 178510232, compound

Procedure

Following the procedure described for [1-(4-azido-5-fluoropyridin-3-yl)-meth-(E)-ylidene]-(2,6-dichloro-4-nitrophenyl)-amine (Example 99, Step 1), 2-amino-3-chloro-5-nitrobenzonitrile was stirred at room temperature to afford the title compound which was used without purification (6.07 g, quantitative yield). LCMS (Method C): RT=3.69 min, m/z: 318 [M+H+−N2].

Sources & evidence

ORD record
ord-d342ec5ea73548178586b8d4ec231f38
Source dataset
uspto-grants-2016_04
Patent number
US09309240B2

Reaction notes

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