Methyl 4-(((1,1-dimethylethoxy)carbonyl)amino)-4-piperidinecarboxylate → {2-[4-(tert-Butoxycarbonylamino)-4-(methoxycarbonyl)piperidin-1-yl]pyrimidin-5-yl}-boronic acid

HRID 626961Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 626961
[C:1]([O:5][C:6]([NH:8][C:9]1([C:15]([O:17][CH3:18])=[O:16])[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl[C:20]1[N:25]=[CH:24][C:23]([B:26]([OH:28])[OH:27])=[CH:22][N:21]=1>>[C:1]([O:5][C:6]([NH:8][C:9]1([C:15]([O:17][CH3:18])=[O:16])[CH2:14][CH2:13][N:12]([C:20]2[N:25]=[CH:24][C:23]([B:26]([OH:28])[OH:27])=[CH:22][N:21]=2)[CH2:11][CH2:10]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Komponenten

3

Edukt 2

HCID 14537079Methyl 4-(((1,1-dimethylethoxy)carbonyl)amino)-4-piperidinecarboxylateHCID 21747362(2-Chloropyrimidin-5-yl)boronic acid

Produkt 1

HCID 131735241{2-[4-(tert-Butoxycarbonylamino)-4-(methoxycarbonyl)piperidin-1-yl]pyrimidin-5-yl}-boronic acid

Versuchsvorschrift

The title compound was synthesised from methyl 4-(tert-butoxycarbonylamino)-piperidine-4-carboxylate and (2-chloropyrimidin-5-yl)boronic acid in accordance with General Method C.

Quellen und Nachweise

ORD-Eintrag
ord-e87f36ca219b498786c36b99469d70c2
Quelldatensatz
uspto-grants-2016_04
Patentnummer
US09309243B2

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