HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Chloropyrimidin-5-yl)boronic acid → {2-[4-(Methylsulfonyl)piperidin-1-yl]pyrimidin-5-yl}boronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Chloropyrimidin-5-yl)boronic acid | HCID 21747362 | — |
| Reactant | 4-(Methanesulfonyl)piperidine | HCID 22275038 | — |
| Product | {2-[4-(Methylsulfonyl)piperidin-1-yl]pyrimidin-5-yl}boronic acid | HCID 131735244 | — |
Reaction Steps
Prepared from 4-(methylsulfonyl)piperidine (0.515 g, 3.16 mmol) and (2-chloropyrimidin-5-yl)boronic acid (0.5 g, 3.16 mmol) in accordance with General Method C to give the title compound as an off-white semi-solid. HPLC-MS: m/z MH+ 286.2, RT 0.17 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309243B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-f3674d9d3b4c4a319438e6d541bf6878 |
| Source note | uspto-grants-2016_04 |