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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 626971Generated: October 31, 2026

(-)-Nipecotic acid → (3R)-1-(5-Boronopyrimidin-2-yl)piperidine-3-carboxylic acid

https://huagongshe.com/reaction/626971

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(-)-Nipecotic acidHCID 1796510—
Reactant(2-Chloropyrimidin-5-yl)boronic acidHCID 21747362—
Product(3R)-1-(5-Boronopyrimidin-2-yl)piperidine-3-carboxylic acidHCID 119087137—

Reaction Steps

The title compound was synthesised from (2-chloropyrimidin-5-yl)boronic acid and (3R)-piperidine-3-carboxylic acid in accordance with General Method C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09309243B2
Source datasetuspto-grants-2016_04
ORD IDord-a2c806682e7342b5a8e57826d7de2b80
Source noteuspto-grants-2016_04