HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-chloro-5-isopropoxy-4-methoxybenzoate → 3-Chloro-5-isopropoxy-4-methoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-chloro-5-isopropoxy-4-methoxybenzoate | HCID 67041761 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Chloro-5-isopropoxy-4-methoxybenzoic acid | HCID 67041762 | 92.7% |
Reaction Steps
3-Chloro-5-isopropoxy-4-methoxybenzoic acid (5) (0.93 g, 89%) was prepared from methyl 3-chloro-5-isopropoxy-4-methoxybenzoate (4) (1.06 g, 4.10 mmol) using a procedure essentially the same as in step (ii) for AAA-001 except that MeOH instead of water was added dropwise until a solution formed: m/z 243 [M−H]− (ES−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447028B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-d4216ef25f214b4daa51ead535c05bab |
| Source note | uspto-grants-2016_09 |