Tert-butyl 4-benzoylpiperidine-1-carboxylate → HCID 86716138, compound

Participants

Reaction Steps

The precursor of the title compound was prepared essentially as described for Example 164, using tert-butyl 4-benzoylpiperidine-1-carboxylate (commercial; e.g., Matrix Scientific) in place of (1-methyl-1H-imidazol-5-yl)(pyridin-4-yl)methanone to provide, after heptanes/acetone flash chromatography, tert-butyl 4-(hydroxy(phenyl)(3-phenyl-2,4-bis(trifluoromethyl)quinolin-6-yl)methyl)piperidine-1-carboxylate as a clear yellow oil.

Provenance & Evidence