2-Amino-4-pentenoic acid → Methyl 2-aminopent-4-enoate--hydrogen chloride (1/1)

HRID 627589Notes

Reaction equation

HRID 627589 reaction equation
[NH2:1][CH:2]([CH2:6][CH:7]=[CH2:8])[C:3]([OH:5])=[O:4].[CH3:9]O.[ClH:11]>>[NH2:1][CH:2]([CH2:6][CH:7]=[CH2:8])[C:3]([O:5][CH3:9])=[O:4].[ClH:11]

Participants

3

Reactant 2

HCID 140442-Amino-4-pentenoic acidHCID 21893726Hydrochloride methanol

Product 1

HCID 11332668Methyl 2-aminopent-4-enoate--hydrogen chloride (1/1)Yield 79.2%

Procedure

A solution of α-Allyl-Gly-OH (1.00 g, 7.75 mmol) in MeOH/HCl (20 mL) was heated at reflux for 3 hrs. After TLC showed the reaction was complete, the mixture was evaporated to give α-Allyl-Gly-OMe HCl (1.10 g, 79.2%).

Workup

  1. temperatureat reflux for 3 hrs
  2. customthe mixture was evaporated

Sources & evidence

ORD record
ord-ba820e9d904241959d30634df0f569b1
Source dataset
uspto-grants-2016_04
Patent number
US09309285B2

Reaction notes

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