Dimethylamine → HCID 118159942, compound

HRID 628284Notes

Reaction equation

HRID 628284 reaction equation
[CH3:1][C:2]1[N:6]2[C:7]3[CH:13]=[C:12]([CH3:14])[N:11]([CH2:15][C:16]4[CH:21]=[CH:20][C:19]([CH2:22]O)=[CH:18][CH:17]=4)[C:8]=3[CH:9]=[CH:10][C:5]2=[N:4][N:3]=1.[CH3:24][NH:25][CH3:26].C1COCC1>>[CH3:1][C:2]1[N:6]2[C:7]3[CH:13]=[C:12]([CH3:14])[N:11]([CH2:15][C:16]4[CH:21]=[CH:20][C:19]([CH2:22][N:25]([CH3:26])[CH3:24])=[CH:18][CH:17]=4)[C:8]=3[CH:9]=[CH:10][C:5]2=[N:4][N:3]=1

Participants

4

Reactant 3

HCID 674DimethylamineHCID 8028TetrahydrofuranHCID 118159705HCID 118159705, compound

Product 1

HCID 118159942HCID 118159942, compound

Procedure

The title compound was prepared according to the procedures of Example 45, using the alcohol of Example 49 as starting material and using 2.0 M dimethylamine in THF (0.15 mL, 0.30 mmol, Aldrich) in the displacement (8.0 mg, 49%).

Sources & evidence

ORD record
ord-473ec6efb5d74ec69cb4ec3f00f1f160
Source dataset
uspto-grants-2016_04
Patent number
US09309246B2

Reaction notes

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