反应详情

A mixture of 1-bromo-2-methyl-3-aminobenzene 25.0 g, triphosgene 60.0 g and toluene 400 ml was stirred with heating under reflux for three hours. The reaction mixture after standing to cool was concentrated under reduced pressure to give 1-bromo-3-isocyanato-2-methylbenzene 30.3 g.

1. temperaturewith heating
2. temperatureunder reflux for three hours
3. temperatureto cool
4. concentrationwas concentrated under reduced pressure