Hydrochloric Acid → HCID 68955545, compound

At 0° C., to a mixture of 3-amino-2-chlorophenol 100 g and concentrated hydrochloric acid 250 ml was added slowly aqueous solution 300 ml containing sodium nitrite 67.0 g and followed by addition of water 400 ml. The resulting mixture was stirred for two hours and thereto was added slowly anhydrous tin(II) chloride 292 g and concentrated hydrochloric acid 250 ml and the resulting mixture was stirred for one hour. At room temperature, the resulting mixture was stirred for additional twelve hours, and then the reaction mixture was filtered and was washed with aqueous 10% hydrochloric acid and hexane to give 2-chloro-4-hydrazinophenol hydrochloride salt 105 g.

1. stirringthe resulting mixture was stirred for one hour
2. stirringAt room temperature, the resulting mixture was stirred for additional twelve hours
3. filtrationthe reaction mixture was filtered
4. washwas washed with aqueous 10% hydrochloric acid and hexane

ORD record

ord-8229694711314489b3aa7684f981195b

Source dataset

uspto-grants-2016_04

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US09314023B2