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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 62862Generated: October 29, 2026

Bromomethylcyclopropane → 6-Cyclopropylmethylsulfanyl-pyridine-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/62862

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromomethylcyclopropaneHCID 81503—
ReactantHCID 178468955HCID 178468955—
Product6-Cyclopropylmethylsulfanyl-pyridine-2-carboxylic acid ethyl esterHCID 9011834981%

Reaction Steps

6-Mercapto-pyridine-2-carboxylic acid ethyl ester (0.54 g, 2.94 mmol) obtained in Step A and bromomethyl cyclopropane were reacted in the same manner as in Step A of Preparation Example 16 to obtain the title compound (0.568 g, 81%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447044B2
Source datasetuspto-grants-2016_09
ORD IDord-de0ae35c9e21402caf8052e30ae81382
Source noteuspto-grants-2016_09