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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 62864Generated: October 26, 2026

Isopropyl iodide → 3-Isopropylsulfanyl-pyrazine-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/62864

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropyl iodideHCID 6362—
ReactantHCID 178499101HCID 178499101—
Product3-Isopropylsulfanyl-pyrazine-2-carboxylic acid methyl esterHCID 9011806861%

Reaction Steps

3-Mercapto-pyrazine-2-carboxylic acid methyl ester (0.35 g, 2.0 mmol) obtained in Step A and 2-iodopropane were reacted in the same manner as in Step A of Preparation Example 5 to obtain the title compound (0.267 g, 61%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447044B2
Source datasetuspto-grants-2016_09
ORD IDord-9c6637ca917049fabc1a23509cbfe685
Source noteuspto-grants-2016_09