HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propanethiol → 2-Isopropylsulfanyl-6-methoxy-nicotinic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propanethiol | HCID 6364 | — |
| Reactant | Methyl 2-chloro-6-methoxynicotinate | HCID 10584232 | — |
| Product | 2-Isopropylsulfanyl-6-methoxy-nicotinic acid methyl ester | HCID 90118211 | 87% |
Reaction Steps
2-Chloro-6-methoxy-nicotinic acid methyl ester (52 mg, 0.26 mmol) obtained in Step B and isopropylthiol were reacted in the same manner as in Step B of Preparation Example 9 to obtain the title compound (54 mg, 87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447044B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-047a99994fcd45d083d8029511e94176 |
| Source note | uspto-grants-2016_09 |