反应详情

温度

80 °C

Part B. A solution of (methyl 4-(3-dimethylamino-acryloyl)-benzoate) (100 mg) in acetic acid (5 mL) is treated with acetophenone and ammonium acetate (77 mg). The resulting mixture is heated to 80° C. for 18 h, then cooled and evaporated under a stream of nitrogen. The resulting solid is recrystallized in ethyl acetate-hexane to afford methyl 3-(6-phenyl-pyridin-2-yl)-benzoate. MS (ES+): m/e 290.2 (100).

1. temperaturecooled
2. customevaporated under a stream of nitrogen
3. customThe resulting solid is recrystallized in ethyl acetate-hexane