HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propanethiol → 4-Isopropylsulfanyl-2-methyl-pyrimidine-5-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propanethiol | HCID 6364 | — |
| Reactant | Methyl 4-chloro-2-methylpyrimidine-5-carboxylate | HCID 83697272 | — |
| Product | 4-Isopropylsulfanyl-2-methyl-pyrimidine-5-carboxylic acid methyl ester | HCID 90118177 | 90% |
Reaction Steps
4-Chloro-2-methyl-pyrimidine-5-carboxylic acid methyl ester (0.105 g, 0.56 mmol) and 2-propanethiol were reacted in the same manner as in Step A of Preparation Example 16 to obtain the title compound (0.114 g, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447044B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-754789530eb34c57855b6617a45abde8 |
| Source note | uspto-grants-2016_09 |