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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 628882Generated: October 29, 2026

Sodium Carbonate → Methyl 4-(6-hydroxyquinolin-2-yl)benzoate

https://huagongshe.com/reaction/628882

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CarbonateHCID 10340—
Reactant4-Methoxycarbonylphenylboronic acidHCID 2734369—
Reactant2-Chloroquinolin-6-olHCID 22132577—
ProductMethyl 4-(6-hydroxyquinolin-2-yl)benzoateHCID 66980069—

Reaction Steps

Scheme 1, step 1, starting from 4-(methoxycarbonyl)phenylboronic acid and 2-chloroquinolin-6-ol, using Na2CO3 instead of TEA.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09315462B2
Source datasetuspto-grants-2016_04
ORD IDord-ea1125c044684100aca845f865cca8fa
Source noteuspto-grants-2016_04