2,4-Difluorophenylboronic acid → 6-Bromo-3-(2,4-difluoro-phenyl)-imidazo[1,2-a]pyridine

Participants

Reaction Steps

The title compound, off-white solid (0.33 g, 49%), MS (ISP) m/z=309.4 [(M+H)+], mp 137.5° C., was prepared in accordance with the general method of intermediate E from commercially available 6-bromo-3-iodoimidazo[1,2-a]pyridine (0.7 g, 2.17 mmol) and commercially available 2,4-difluoro-phenylboronic acid (0.38 g, 2.38 mmol).

Provenance & Evidence